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Luis Felipe Barraza Ramírez

ACADEMICO-INVESTIGADOR

Universidad San Sebastián

Valdivia, Chile

Dendrimers as a drug delivery system; Computational Chemistry; Molecular Dynamics, Advanced NMR, Supramolecular Chemistry, Functional Nanoparticles, Photodynamic Therapy for treatment of cancer and infectious diseases.

LICENCIATURA EN QUIMICA, UNIVERSIDAD DE CONCEPCION. Chile, 2010
Doctorado en Ciencias c/m en Química, UNIVERSIDAD DE CONCEPCION. Chile, 2015
QUIMICO, UNIVERSIDAD DE CONCEPCION. Chile, 2010

graduate student (candidate for academic degree of Dr. in Chemistry) Part Time

UNIVERSIDAD DE CONCEPCION

FACULTAD DE CIENCIAS QUIMICAS

CONCEPCION, Chile

2011 - 2015
ACADÉMICO-INVESTIGADOR Part Time

UNIVERSIDAD ANDRES BELLO

FACULTAD DE CIENCIAS EXACTAS

CONCEPCION, Chile

2015 - 2023
Docente-Investigador Full Time

UNIVERSIDAD SAN SEBASTIAN

Medicina y Ciencia

Valdivia, Chile

2023 - A la fecha

Asistente Técnico Part Time

UNIVERSIDAD DE CONCEPCION

Concepción, Chile

2008 - 2008
ACADEMICO PLANTA ADJUNTA Part Time

UNIVERSIDAD ANDRES BELLO

CONCEPCION, Chile

2015 - 2023


Self-assembled PAMAM-G4 dendrimer nanoparticles with Phloxine B as photosensitizer for antimicrobial photodynamic therapy Ybarra, DE; Quezada, C.; Guarín, YA; Cabello G.A.; Montanari, J; Alvira, FC; Alonso, SD; Meléndrez M.F.; Barraza, LF Article ISI INTERNATIONAL JOURNAL OF PHARMACEUTICS (2025)
Dual-Action Gemcitabine Delivery: Chitosan-Magnetite-Zeolite Capsules for Targeted Cancer Therapy and Antibacterial Defense Guarín-González, YA; Cabello-Guzman, G; Reyes-Gasga, J; Moreno-Navarro, Y; Vergara-Gonzalez, L.; Martin-Martin, A; López-Muñoz, R; Cardenas-Trivino, G; Barraza, LF Article ISI GELS (2024)
Multifunctional nano-in-microparticles for targeted lung cancer cells: Synthesis, characterization and efficacy assessment Guarin-Gonzalez, Yuly Andrea; Plessing, Carlos Von; Rio, Rodrigo Segura -del; Barraza, Luis; Marti-Martin, Antonia Article ISI SCOPUS MATERIALS TODAY CHEMISTRY (2024)
Surface-enhanced Raman sensor with molecularly imprinted nanoparticles as highly sensitive recognition material for cancer marker amino acids Samhitha, Shiva; Ges, Adrian; Blanco-Lopez, Maria Carmen Article ISI TALANTA (2024)
Molecularly imprinted nanoparticle-based assay (MINA) for microcystin-LR detection in water Sanchez, Susana Article ISI ANALYST (2023)
Vismodegib in PAMAM-dendrimers for potential theragnosis in skin cancer Article SCOPUS OpenNano (2022)
Molecularly imprinted nanoparticle-based assay (MINA): Potential application for the detection of the neurotoxin domoic acid Quezada, Camila Article ISI ANALYTICA CHIMICA ACTA (2021)
Cytotoxicity and in vivo plasma kinetic behavior of surface-functionalized PAMAM dendrimers Benitez, Carolina; Barraza, Luis F.; Guzmán, Leonardo; Fuentealba, Jorge; Alderete, Joel B. Article ISI SCOPUS NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2018)
Effect of pH on Eosin Y/PAMAM interactions studied from absorption spectroscopy and molecular dynamics simulations Barraza, LF; Alderete, JB; Arbeloa, EM; Jiménez, VA Article ISI SCOPUS JOURNAL OF LUMINESCENCE (2018)
Association of Methotrexate with Native and PEGylated PAMAM-G4 Dendrimers: Effect of the PEGylation Degree on the Drug-Loading Capacity and Preferential Binding Sites Jim?nez, Ver?nica A. Article ISI SCOPUS Journal of Physical Chemistry B (2017)
Methotrexate Complexation with Native and PEGylated PAMAM-G4: Effect of the PEGylation Degree on the Drug Loading Capacity and Release Kinetics Barraza, LF; Jiménez, VA; Alderete, JB Article ISI SCOPUS MACROMOLECULAR CHEMISTRY AND PHYSICS (2016)
Effect of PEGylation on the Structure and Drug Loading Capacity of PAMAM-G4 Dendrimers: A Molecular Modeling Approach on the Complexation of 5-Fluorouracil with Native and PEGylated PAMAM-G4 Barraza, LF; Jiménez, VA; Alderete, JB Article ISI SCOPUS Macromolecular Chemistry and Physics (2015)
Complexation of Mefenamic Acid by Low-Generation PAMAM Dendrimers: Insight from NMR Spectroscopy Studies and Molecular Dynamics Simulations Barra, Pabla A.; Barraza, Luis; Jimenez, Veronica A.; Gavín, José A.; Alderete, Joel B. Article ISI SCOPUS MACROMOLECULAR CHEMISTRY AND PHYSICS (2014)
Drug-dendrimer supramolecular complexation studied from molecular dynamics simulations and NMR spectroscopy Barra, Pabla A.; Barraza, Luis F.; Jimenez, Veronica A.; Gavín, José A.; Alderete, Joel B. Article ISI SCOPUS STRUCTURAL CHEMISTRY (2014)
Diffusion coefficients of first-generation polyamidoamine dendrimer and its beta-cyclodextrin conjugate in aqueous solution by means of molecular dynamics simulations Alderete, J. B. Article ISI SCOPUS Monatshefte fur Chemie (2012)


Proceso para obtención de geles biocompatibles antimicrobianos en un solo paso con nanopartículas encapsuladas BERRIO NIÑO, María Elizabeth; JEREZ OLATE, Cristian; Meléndrez Castro, Manuel Francisco; BARRAZA RAMÍREZ, Luis Felipe; Quezada Mella, Camila Constanza; Palacio Badel, Daniel Andrés; SÁNCHEZ SANHUEZA, Gabriela Alejandra Patent (2025)


SELF-ASSEMBLY AS NOVEL STRATEGY TO OBTAIN PAMAM-BASED PHOTOSENSITIZER NANOPARTICLES. STRUCTURE, THERMODYNAMICS AND EVALUATION OF THE NANOPARTICLES AS DRUG-DELIVERY SYSTEMS FOR COMBINED CHEMO-PHOTODYNAMIC THERAPY Luis Felipe Barraza Proyecto (2020)
Dendrimers as drug delivery systems for combinatorial chemotherapy. New insight of complexation and release mechanism. FONDECYT (3160378) Proyecto 2015-2018 Inv. Responsable
HOST -GUEST CHEMISTRY OF CONJUGATE PAMAM DENDRIMER NANOCARRIERS FONDECYT (1130531) Proyecto 2013-2016 Tesista
STRUCTURE-PROPERTY RELATIONSHIPS FOR THE COMPLEXATION OF ORGANIC GUESTS WITH CYCLODEXTRIN-DENDRIMER CONJUGATES FONDECYT (1080282) Proyecto 2008-2012 Personal técnico y/o de apoyo
STRUCTURE-PROPERTY RELATIONSHIPS FOR THE COMPLEXATION OF ORGANIC GUESTS WITH CYCLODEXTRIN-DENDRIMER CONJUGATES FONDECYT (1080282) Proyecto 2008-2012 Tesista


Sensors Based on Molecularly Imprinted Polymers in the Field of Cancer Biomarker Detection: A Review Samhitha, S. Shiva; Medina, Carlos Review ISI NANOMATERIALS (2024)