PDI - Resultado de Búsqueda

Alejandra Margarita Herrera Morandé

PROFESORA ASISTENTE

Universidad Autónoma de Chile

TALCA, Chile

BIOQUIMICA; BIOLOGIA ESTRUCTURAL; ENZIMOLOGIA

Doctorado en Biotecnología, UNIVERSIDAD DE BARCELONA. España, 2015
Bioquimica, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2007
Biotecnología Molecular, UNIVERSIDAD DE BARCELONA. Chile, 2010

POSTDOCTORADO Full Time

UNIVERSIDAD DE CHILE

CIENCIAS

SANTIAGO, Chile

2015 - 2018
PROFESORA DE LABORATORIO BIOQUIMICA Part Time

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

2016 - 2018
POSTDOCTORADO Full Time

UNIVERSIDAD DE SANTIAGO DE CHILE

Química y Biología

SANTIAGO, Chile

2019 - 2019
POSTDOCTORADO Full Time

INSTITUTE FOR RESEARCH IN BIOMEDICINE

Barcelona, España

2019 - 2019
PROFESORA ASISTENTE Full Time

UNIVERSIDAD AUTONOMA DE CHILE

INGENIERIA

TALCA, Chile

2023 - A la fecha

Personal Docente

Universidad de Chile

Chile

2012 - 2014


Theoretical evaluation of a bulky ortho-thioalkyl-azobenzene as an alternative to photocontrol structural cytotoxic effects of metal-free and disulfide oxidized hSOD1 in pathogenesis of ALS Galaz-Araya, C; Zuñiga- Núñez, D; Salas-Sepúlveda, F; Herrera-Morande, A; Aspée A.; Poblete, H.; Zamora R.A. Article ISI RSC ADVANCES (2025)
Structure and inhibition of SARS-CoV-1 and SARS-CoV-2 main proteases by oral antiviral compound AG7404 Montserrat Fàbrega-Ferrer; Alejandra Herrera-Morandé; Sara Muriel-Goñi; Julia Pérez-Saavedra; Paula Bueno; Victoria Castro; Urtzi Garaigorta; Pablo Gastaminza; Miquel Coll Article ANTIVIRAL RESEARCH (2022)
Free radicals derived from ?-radiolysis of water and AAPH thermolysis mediate oxidative crosslinking of eGFP involving Tyr-Tyr and Tyr-Cys bonds: the fluorescence of the protein is conserved only towards peroxyl radicals Zamora R.A.; Mura F.; Rojas, T Article ISI SCOPUS Free Radical Biology and Medicine (2020)
Tuning of Conformational Dynamics Through Evolution-Based Design Modulates the Catalytic Adaptability of an Extremophilic Kinase Villalobos, Pablo; Maturana, Pablo Article ACS CATALYSIS (2020)
Protein topology determines substrate-binding mechanism in homologous enzymes Merino F.; RamÃrez-Sarmiento C.A.; GuixÃ© V. Article ISI SCOPUS Biochimica et Biophysica Acta - General Subjects (2018)
Protein topology determines substrate-binding mechanism in homologous enzymes A. Herrera-Morande, V. Castro-Fernandez; F. Merino, C.A. Ramírez-Sarmiento; F.J. Fernández, M.C. Vega Article Biochemical & Biophysics Acta- General Subject (2018)
Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases Padilla-Salinas F.; Brandão-Neto J. Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Bifunctional ADP-dependent phosphofructokinase/ glucokinase activity in the order Methanococcales biochemical characterization of the mesophilic enzyme from Methanococcus maripaludis Castro-Fernandez, Victor; Bravo-Moraga, Felipe; Herrera-Morande, Alejandra; Guixé, Victoria Article ISI SCOPUS FEBS JOURNAL (2014)
Crystal Structure, SAXS and Kinetic Mechanism of Hyperthermophilic ADP-Dependent Glucokinase from Thermococcus litoralis Reveal a Conserved Mechanism for Catalysis Rivas-Pardo, JA; Herrera-Morande, A; Castro-Fernandez, V; Vega, MC; Guixé, V Article ISI SCOPUS PLOS ONE (2013)


Folding topology determines substrate binding order in the ribokinase superfamily Herrera-Morande, A; Castro-Fernandez, V; Merino F.; Ramirez-Sarmiento, C; Fernández F.; Vega, C; Guixé, V Abstract ISI PROTEIN SCIENCE (2015)
Ligands-induced catalytically relevant structural transitions of ADP-dependent glucokinase in the crystalline state and in solution Guixé, V; Rivas-Pardo, JA; Herrera-Morande, A; Fernández F.; Vega, MC Abstract ISI PROTEIN SCIENCE (2012)


Generación y caracterización de VLPs de Piscine Reovirus de Salmon como posible prototipo de vacuna Proyecto postdoctorado DICYT-USACH (cod021943CSM,) Proyecto 2019-2019 Inv. Responsable
X-Ray diffractions of proteins from a Chilean Crystallization Facility (continuation of prior proposal) Brazilian Center for research in energy and materials (20180298) Proyecto 2019-2019 Inv. Responsable
Red Chilena de Cristalografía de proteínas PCI (REDI170497) Proyecto 2017-2019 Investigador(a)
X-Ray Diffraction of proteins from a Chilean Crystallization Facility Brazilian Center for research in ennergy and materials (Proposer ID=> 20170963) Proyecto 2017-2017 Inv. Responsable
Análisis estructural y funcional de la gucoquinasa dependiente de ADP de Homo Sapiens FONDECYT (3160373) Proyecto 2016-2019 Inv. Responsable
EVOLUTION OF RIBOKINASE SUPERFAMILY ENZYMES=> STRUCTURE-FUNCTION RELATIONSHIPS THAT DETERMINE SUBSTRATE SPECIFICITY, METAL ASSISTED MECHANISM AND PROTEIN STABILITY. FONDECYT (1110137) Proyecto 2011-2015 Tesista
Phylogeny, catalytic mechanism, and substrate specificity of enzymes from the ribokinase superfamily. Implications for the evolution of the superfamily. FONDECYT (107011) Proyecto 2009-2012 Tesista
MECANISMO CATALITICO DE LA CARBOXIQUINASA FOSFOENOLPIRUVICA DE SACCHAROMYCES CEREVISIAE. FONDECYT (1070202) Proyecto 2007-2011 Tesista