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Christina Schuh

Associate Professor

Universidad del Desarrollo

Santiago, Chile

Líneas de Investigación


Novel sources of extracellular vesicles; Biomaterials; wound healing; Revalorization of waste materials

Educación

  •  Tissue Engineering in Technical Sciences, Vienna University of Technology. Austria, 2016
  •  Biomedical Engineering Sciences, UAS Technikum Wien. Austria, 2012
  •  Biomedical Engineering, UAS Technikum Wien. Austria, 2010

Experiencia Académica

  •   PhD student Full Time

    Ludwig Boltzmann Institute for experimental and clinical Traumatology

    Vienna, Austria

    2013 - 2016

  •   Postdoctoral Researcher Full Time

    University College London

    Medical Sciences

    London, Reino Unido

    2016 - 2016

  •   Junior Group Leader Other

    Ludwig Boltzmann Institute for experimental and clinical Traumatology

    Vienna, Austria

    2014 - 2017

  •   Postdoctoral Researcher Full Time

    UNIVERSIDAD DE LOS ANDES

    Medicine

    Santiago, Chile

    2017 - 2018

  •   Assistant Professor Full Time

    UNIVERSIDAD DEL DESARROLLO

    Medicine

    Santiago, Chile

    2019 - 2024

  •   Postdoctoral Researcher Full Time

    Ludwig Boltzmann Institute for experimental and clinical Traumatology

    Vienna, Austria

    2016 - 2017

  •   Associate Professor Full Time

    UNIVERSIDAD DEL DESARROLLO

    Medicine

    Chile

    2024 - A la fecha

Experiencia Profesional

  •   Postdoctoral Researcher Full Time

    Cells for Cells

    Santiago, Chile

    2018 - 2019

  •   Research Assistant Part Time

    UAS Technikum Wien

    Austria

    2008 - 2013

  •   Teacher for Science Education Part Time

    TGM School of Technology

    Vienna, Austria

    2012 - 2017

Formación de Capital Humano


2025-present: Alfonso Miranda
Doctorate program “Science and Innovation in Medicine”, Universidad del Desarrollo;
2023-2024: Cecilia Tapia (graduated)
Undergraduate program “Tecnología Medica”, Universidad del Desarrollo; Thesis: “Evaluación de actividad antimicrobiana de las vesículas extracelulares extraídas de la hoja de la planta Buddleja globosa Hope (Matico)”
2023-present: Ana Maria Gonzalez
Doctorate program “Science and Innovation in Medicine”, Universidad del Desarrollo; Thesis: “Caracterización de Vesículas de Membrana Externa (OMVs) de Klebsiella pneumoniae y su Impacto en la Resistencia Antibiótica.“
2021-2024: Javiera Carrasco (graduated)
Doctorate program “Science and Innovation in Medicine”, Universidad del Desarrollo; “Exosomas miméticos derivados de células Natural Killer como vehículos de fármacos antineoplásicos y una alternativa inmunoterapéutica para el cáncer de pulmón multirresistente”
2019- present: Orlando Ramírez
Doctorate program “Science and Innovation in Medicine”, Universidad del Desarrollo; “Desarrollo de un sistema de nano-transporte basado en hidrogeles y vesículas extracelulares vegetales provenientes de plantes chilenas para el tratamiento de heridas crónicas”
2023: Francisco Peña Osorio (graduated)
Undergraduate program “Civil Engineering, Major in Biomedical Engineering”, Pontificia Universidad Catolica de Chile; “Automated quantitative analysis of traction force microscopy”
2019/2020: Camila Leiva Sabadini (graduated)
Biochemistry Undergraduate, Pontificia Universidad Católica, Thesis: Inhibitory effect of Apis mellifera honey extracellular vesicles on oral biofilms
2015/2016: Lennard Fischer-See (graduated)
Biomedical Engineering Sciences at UAS Technikum Wien, Thesis: Extracorporeal Shockwave Treatment and Low Level Light Therapy: Comparison of physical stimuli on neuronal cells
2014/2015: Ciara Almeria (graduated)
Biomedical Engineering Sciences at UAS Technikum Wien, Thesis: Stem cell behavior on electrospun small vessel grafts
2013/2014: Max Horvath (graduated)
Biomedical Engineering Sciences at UAS Technikum Wien, Thesis: Schwann cells of the peripheral nervous system after injury


Premios y Distinciones

  •   Dr Maria Schaumayer Award for outstanding scientific papers

    Dr Maria Schaumayer Society

    Austria, 2017

    Award by the Dr. Maria Schaumayer Society for the PhD Thesis "Tissue engineering approaches to improve peripheral nerve regeneration"

  •   Günther Schlag Memorial Award

    Ludwig Boltzmann Society

    Chile, 2014

    Award for innovative research in regenerative medicine, research paper: "Extracorporeal Shockwave Treatment activates Schwann cells in vitro and in vivo"

  •   TERMIS-AM Neural and Spine TWIG award

    Tissue Engineering and Regenerative Medicine International Society

    Estados Unidos, 2015

    Award by the TERMIS Thematic Working Interest Group "Neural and Spine" for the research paper "Extracorporeal Shockwave Treatment accelerates peripheral nerve regeneration by altering Schwann cell phenotype", presented at the 2015 TERMIS World Congress, Boston, US.


 

Article (29)

Artificial cell-derived vesicles by extrusion, a novel docetaxel drug delivery system for lung cancer
NLC-Based Rifampicin Delivery System: Development and Characterization for Improved Drug Performance Against Staphylococcus aureus
Royal jelly derived extracellular vesicles modulate microglial nanomechanics and inflammatory responses
A Natural deep eutectic solvent as an effective material for dual debridement and antibiofilm effects in chronic wound treatment
Aloe vera peel-derived nanovesicles display anti-inflammatory properties and prevent myofibroblast differentiation
Microfabrication-based engineering of biomimetic dentin-like constructs to simulate dental aging
Modulation of the biophysical and biochemical properties of collagen by glycation for tissue engineering applications
Nanoscale Dynamics of Streptococcal Adhesion to AGE-Modified Collagen
Royal jelly extracellular vesicles promote wound healing by modulating underlying cellular responses
Nanomechanical and Molecular Characterization of Aging in Dentinal Collagen
Ultrastructural characterisation of young and aged dental enamel by atomic force microscopy
Antibacterial Effect of Honey-Derived Exosomes Containing Antimicrobial Peptides Against Oral Streptococci
Bacterial adhesion to collagens: implications for biofilm formation and disease progression in the oral cavity
Modulatory Effect of Glycated Collagen on Oral Streptococcal Nanoadhesion
Complex Interaction between Resident Microbiota and Misfolded Proteins: Role in Neuroinflammation and Neurodegeneration
Motor and sensory Schwann cell phenotype commitment is diminished by extracorporeal shockwave treatment in vitro
Type I collagen hydrogels as a delivery matrix for royal jelly derived extracellular vesicles
Exosome-like vesicles in Apis mellifera bee pollen, honey and royal jelly contribute to their antibacterial and pro-regenerative activity
Exosomes on the border of species and kingdom intercommunication
Spatiotemporal Differences in Gene Expression Between Motor and Sensory Autografts and Their Effect on Femoral Nerve Regeneration in the Rat
An Optimized Collagen-Fibrin Blend Engineered Neural Tissue Promotes Peripheral Nerve Repair
The reparative abilities of menstrual stem cells modulate the wound matrix signals and improve cutaneous regeneration
Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy
Covalent binding of placental derived proteins to silk fibroin improves schwann cell adhesion and proliferation
Extracorporeal shockwave treatment: A novel tool to improve Schwann cell isolation and culture
IMPROVED OSTEOGENIC VECTOR FOR NON-VIRAL GENE THERAPY
A New Preparation Method for Anisotropic Silk Fibroin Nerve Guidance Conduits and Its Evaluation In Vitro and in a Rat Sciatic Nerve Defect Model
Activated Schwann Cell-Like Cells on Aligned Fibrin-Poly(Lactic-Co-Glycolic Acid) Structures: A Novel Construct for Application in Peripheral Nerve Regeneration
In vitro extracorporeal shock wave treatment enhances stemness and preserves multipotency of rat and human adipose-derived stem cells

Abstract (2)

Glycation Promotes Oral Biofilm Formation On Microfabricated Bioengineered Dentin Substrates
SAFETY AND EFFICACY PROFILE OF CRYOPRESERVED MESENCHYMAL STEM CELLS FOR THE TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME.

BookSection (1)

The Role of Schwann Cells in Peripheral Nerve Function, Injury, and Repair

Proyecto (8)

Combining nano-mechanobiology and biomedicine to elucidate the anti-inflammatory effect of Apis mellifera derived Royal Jelly Extracellular Vesicles in neuroinflammation
Silk-PEV: a nano-delivery based wound patch to reduce inflammation and scarring in second-degree burn wounds
Analysis of Antimicrobial and Pro regenerative Properties of Exosomes Derived from Apis mellifera Royal Jelly
Implementación de un método de producción, concentración y aislamiento de exosomas para medicina regenerativa
Influence of age-derived dental collagen glycation on bacterial adhesion and initial biofilm formation of oral streptococci
Desarrollo y validación de un producto celular alogénico derivado de células madre estromales para su uso en síndrome de distrés respiratorio agudo
Liporegeneration
newTissue- novel approaches for Tissue Engineering

Review (2)

Potential Novel Strategies for the Treatment of Dental Pulp-Derived Pain: Pharmacological Approaches and Beyond
Association between Alzheimers Disease and Oral and Gut Microbiota: Are Pore Forming Proteins the Missing Link?
2
Maroun Khoury

Professor

Faculty of Medicine

Universidad de Los Andes

santiago, Chile

1
Benjamin Vicente

Director de Departamento

Psiquiatría y Salud Mental

FACULTAD DE MEDICINA UNIVERSIDAD DE CONCEPCION

CONCEPCION, Chile

1
Eduardo Ezquer

Director/Full Professor

Centro de Medicina Regenerativa

UNIVERSIDAD DEL DESARROLLO, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS

Santiago, Chile

4
Nelson Barrera

Associate Professor

Physiology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Jimena Cuenca

Investigador/profesor

Facultad de Medicina

Universidad de Los Andes

Santiago, Chile

1
Francisca Alcayaga

Profesor Asociado

Facultad de Medicina

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

2
gabriela zavala

Investigador post-doctoral

Cells for Cells

Universidad de los Andes

Santiago, Chile

2
Bruna Benso

Profesora Asistente

Facultad de Medicina

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Fabián Martínez

Académico

Ciencias del Ambiente

Universidad de Santiago de Chile

Santiago, Chile

2
Maria Olivares

Docente Investigador

Instituto de Ciencias e Innovación en Medicina

Universidad del Desarrollo

Santiago, Chile

1
Javier Morales

Profesor Asociado

Departamento de Ciencias y Tecnología Farmacéuticas

Universidad de Chile

Santiago, Chile

9
Sebastián Aguayo

Assistant Professor

Dentistry

Pontificia Universidad Católica de Chile

Santiago, Chile

37
Christina Schuh

Associate Professor

Centre for Regenerative Medicine

Universidad del Desarrollo

Santiago, Chile

5
simon alvarez

Instructor Adjunto

Facultad de Odontología

Universidad Andrés Bello

Santiago, Chile